Calcium-oligochitosan-pectin microcarrier for colonic drug delivery

Autor:	Wujie Zhang, Junhong Chen, Alexander Dyble, Douglas A. Steeber, Rebecca L. Majewski, Kendra Lehman, M. Kaltchev, Xiaoru Guo, Michael J. Wedemeyer, Samuel Stealey
Rok vydání:	2019
Předmět:	food.ingredient Pectin Colon Chemistry Pharmaceutical Oligosaccharides Pharmaceutical Science chemistry.chemical_element Chitin macromolecular substances 02 engineering and technology Calcium Pharmacology complex mixtures 030226 pharmacology & pharmacy 03 medical and health sciences Drug Delivery Systems 0302 clinical medicine food Upper gastrointestinal Chitosan Drug Carriers Chemistry Microcarrier General Medicine Hydrogen-Ion Concentration 021001 nanoscience & nanotechnology digestive system diseases Pharmaceutical Preparations Solubility Drug delivery Pectins 0210 nano-technology
Zdroj:	Pharmaceutical Development and Technology. 25:260-265
ISSN:	1097-9867 1083-7450
Popis:	Pectin-based hydrogel microcarriers have shown promise for drug delivery to the colonic region. Microcarriers must remain stable throughout the upper gastrointestinal tract for effective colonic delivery, an issue that traditional pectin-based microcarriers have faced. The positively-charged natural biopolymer oligochitosan and divalent cation Ca
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccbe201bdeac00d041935bb9d3a9437 https://doi.org/10.1080/10837450.2019.1691591 Zobrazit plný text záznamu