H. pylori Infection, Inflammation and Gastric Cancer
| Autor: | Roohi Rasool, G. M. Gulzar, Zafar A. Shah, Sameer Naqash, Qurteeba Qadri |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Inflammation
Helicobacter pylori business.industry medicine.medical_treatment Gastroenterology Cancer H pylori infection medicine.disease Helicobacter Infections Radiation therapy Chronic infection Cell Transformation Neoplastic Oncology Stomach Neoplasms Immunology medicine Humans medicine.symptom business |
| Zdroj: | Journal of Gastrointestinal Cancer. 45:126-132 |
| ISSN: | 1941-6636 1941-6628 |
| Popis: | A strong association between chronic infection, inflammation, and cancer has been suggested.Helicobacter pylori, a microaerophilic gram negative bacterium, infects about half the world's population. It has been defined as a definitive carcinogen in the pathogenesis of gastric cancer. H. pylori evades the host immune responses and persists in the stomach leading to gastritis gastric atrophy and sometimes gastric cancer.Chronic H. pylori infection causes gastric cancer via two mechanisms: the presence of virulence factors and the induction of chronic inflammation which ultimately leads to neoplastic transformation. |
| Databáze: | OpenAIRE |
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