Human parvovirus B19: Immunity of Greek females and prenatal investigation of hydrops fetalis
| Autor: | Maria Simitsopoulou, John Bondis, F. Frantzidou, Vassiliki Kyriazopoulou, Athanasios Athanasiadis, E. Diza, Efimia Souliou |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Amniotic fluid Hydrops Fetalis animal diseases viruses Population Erythema Infectiosum Enzyme-Linked Immunosorbent Assay Prenatal diagnosis Antibodies Viral Polymerase Chain Reaction Serology Pregnancy Prenatal Diagnosis Hydrops fetalis Parvovirus B19 Human Humans Medicine education DNA Primers Parvoviridae Fetus education.field_of_study Base Sequence Greece biology business.industry Parvovirus virus diseases Obstetrics and Gynecology Amniotic Fluid biology.organism_classification medicine.disease Blotting Southern Immunoglobulin M Reproductive Medicine Immunoglobulin G DNA Viral Immunology Female business |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 74:157-160 |
| ISSN: | 0301-2115 |
| DOI: | 10.1016/s0301-2115(97)00107-3 |
| Popis: | Sera from 308 healthy Greek females of reproductive age were examined for specific IgG antibodies to human parvovirus B19 by recombinant-Elisa to determine the immunity rates of this part of population to parvovirus B19. Also paired maternal sera and amniotic fluids from nine pregnancies with hydrops fetalis were investigated for specific IgG and IgM antibodies and parvovirus DNA by polymerase chain reaction and southern hybridization analysis. The latter study was conducted to find out the participation of parvovirus B19 infection in hydrops fetalis cases in Greece. The overall prevalence of IgG antibodies in healthy Greek females was at a rate of 57.8% rising with age. One case of hydrops fetalis out of the nine examined, was diagnosed prenatally as parvovirus B19 maternal-fetal infection. It was a twin pregnancy with one fetus hydropic and the other growth retarded. Premature birth of liveborn infants was followed by neonatal death, 48 h after delivery. The contribution of parvovirus B19 in cases of non-immune hydrops fetalis was at 11% in this part of the world. |
| Databáze: | OpenAIRE |
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