The cardiovascular aspects of a Ménière's disease population – A pilot study
| Autor: | Cecília Almeida e Sousa, Sandra Sousa e Castro, Telma Feliciano, David Dias, Ângela Reis Rego, Ana Nóbrega Pinto |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pediatrics
medicine.medical_specialty Ménière disease Population Disease Atopy 03 medical and health sciences 0302 clinical medicine Medicine Risk factor 030223 otorhinolaryngology education Autoimmune disease education.field_of_study business.industry Cardiovascular disease Prognosis medicine.disease lcsh:Otorhinolaryngology lcsh:RF1-547 Otorhinolaryngology Migraine Hypertension business 030217 neurology & neurosurgery Research Article Rare disease Meniere's disease |
| Zdroj: | Journal of Otology, Vol 14, Iss 2, Pp 51-56 (2019) Journal of Otology |
| ISSN: | 1672-2930 |
| Popis: | Introduction: MD is considered a rare disease. An adequate model that explains MD's pathophysiology is not well established. Recently, the vascular theory of the disease has been revived. Objectives: To characterize a MD population according to its cardiovascular risk and correlate it to the MD clinical course. Methods: In this retrospective chart study the data of 31 MD patients observed between January 2017 and April 2018 in a tertiary university hospital were reviewed. Patients included in the study were diagnosed according to the Bárány Society criteria. Lost follow-ups, patients with autoimmune disease, atopy or allergy, major psychiatric disease and migraine were excluded. Age, gender, cardiovascular risk factors, audiometric and vestibular parameters, occurrence of MD attacks in the previous 6 months, vestibular medication in course and time course of MD were recorded and compared between groups (with and without cardiovascular risk factors). Results: 31 patients (61.3% females) mean aged 60.3 years (±9.7) were studied. 74% of the population had at least one risk factor and 51.6% of patients had attacks in the last 6 months. There was a statistically significant difference in the occurrence of MD attacks in the last 6 months (p = 0.014) between MD patients with and without risk factors. Mean PTA thresholds were higher and speech discrimination was lower in individuals with more cardiovascular risk factors. Conclusions: Treatment of MD focusing on vascular risk factors may allow a better control of symptoms and result in a decreased need for ablative procedures in this disorder. Keywords: Ménière disease, Cardiovascular disease, Hypertension, Prognosis |
| Databáze: | OpenAIRE |
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