Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson's disease
| Autor: | W. M. Michael Schüpbach, Joseph-André Ghika, Alain Kaelin-Lang, Markus Florian Oertel, Michael Fiechter, Lennart Stieglitz, Andreas Raabe, Claudio Pollo |
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| Přispěvatelé: | University of Zurich, Oertel, Markus F |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Deep brain stimulation Neurology Parkinson's disease Deep Brain Stimulation medicine.medical_treatment 610 Medicine & health Stimulation Audiology Simultaneous stimulation 10180 Clinic for Neurosurgery 03 medical and health sciences 0302 clinical medicine Subthalamic Nucleus Tremor Humans Medicine Tremor dominant Aged Ventral Thalamic Nuclei business.industry Parkinson Disease biochemical phenomena metabolism and nutrition medicine.disease 2746 Surgery nervous system diseases Subthalamic nucleus 2728 Neurology (clinical) 030104 developmental biology surgical procedures operative nervous system Surgery Neurology (clinical) Neurosurgery business Neuroscience therapeutics 030217 neurology & neurosurgery |
| Zdroj: | Oertel, Markus Florian; Schüpbach, Michael; Ghika, Joseph-André; Stieglitz, Lennart H; Fiechter, Michael; Kaelin, Alain; Raabe, Andreas; Pollo, Claudio (2017). Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson's disease. Acta neurochirurgica, 159(2), pp. 265-269. Springer 10.1007/s00701-016-3044-5 |
| DOI: | 10.7892/boris.92285 |
| Popis: | Deep brain stimulation (DBS) in the thalamic ventral intermediate (Vim) or the subthalamic nucleus (STN) reportedly improves medication-refractory Parkinson's disease (PD) tremor. However, little is known about the potential synergic effects of combined Vim and STN DBS. We describe a 79-year-old man with medication-refractory tremor-dominant PD. Bilateral Vim DBS electrode implantation produced insufficient improvement. Therefore, the patient underwent additional unilateral left-sided STN DBS. Whereas Vim or STN stimulation alone led to partial improvement, persisting tremor resolution occurred after simultaneous stimulation. The combination of both targets may have a synergic effect and is an alternative option in suitable cases. |
| Databáze: | OpenAIRE |
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