Synthesis and Phytotoxic Evaluation of Isatin Derivatives Supported by 3D-QSAR Study
Autor: | Pedro Alves Bezerra Morais, Karolinni B. Britto, Evandro Messias, Peterson de Andrade, Elias Werner, Adilson Vidal Costa, Valdemar Lacerda, Christiano Jorge Gomes Pinheiro, Heberth de Paula, Warley de Souza Borges |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Journal of Agricultural and Food Chemistry. 71:255-266 |
ISSN: | 1520-5118 0021-8561 |
DOI: | 10.1021/acs.jafc.2c06500 |
Popis: | Concerned about weed infestation, a major threat to food production and herbicide resistance that interferes in the mechanism of action of the main herbicides, we have synthesized eight isatin derivatives using the "Click Chemistry" approach through copper-catalyzed azide-alkyne cycloadditions (CuAAC). Sixteen isatin derivatives were evaluated for their phytotoxic activity against the seed culture of the model plants |
Databáze: | OpenAIRE |
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