Synthesis and Phytotoxic Evaluation of Isatin Derivatives Supported by 3D-QSAR Study

Autor: Pedro Alves Bezerra Morais, Karolinni B. Britto, Evandro Messias, Peterson de Andrade, Elias Werner, Adilson Vidal Costa, Valdemar Lacerda, Christiano Jorge Gomes Pinheiro, Heberth de Paula, Warley de Souza Borges
Rok vydání: 2022
Předmět:
Zdroj: Journal of Agricultural and Food Chemistry. 71:255-266
ISSN: 1520-5118
0021-8561
DOI: 10.1021/acs.jafc.2c06500
Popis: Concerned about weed infestation, a major threat to food production and herbicide resistance that interferes in the mechanism of action of the main herbicides, we have synthesized eight isatin derivatives using the "Click Chemistry" approach through copper-catalyzed azide-alkyne cycloadditions (CuAAC). Sixteen isatin derivatives were evaluated for their phytotoxic activity against the seed culture of the model plants
Databáze: OpenAIRE