OMICS approaches in cardiovascular diseases: a mini review
| Autor: | Syaefudin Ali Akhmad, Saleh Muhammed Raqib, Md. Mehadi Hasan Sohag |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
business.industry
Mini Review Early detection Health Informatics Genomics Computational biology Omics Proteomics metabolomics Mini review cardiovascular diseases transcriptomics Metabolomics proteomics Genetics genomics Medicine Prognostics OMICS business Ecology Evolution Behavior and Systematics Early onset |
| Zdroj: | Genomics & Informatics |
| ISSN: | 2234-0742 1598-866X |
| Popis: | Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry which could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect. |
| Databáze: | OpenAIRE |
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