Melatonin counteracts necroptosis and pulmonary edema in cadmium-induced chronic lung injury through the inhibition of angiotensin II
| Autor: | Sushweta Mahalanobish, Sukanya Saha, Sayanta Dutta, Sumit Ghosh, Parames C. Sil |
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| Rok vydání: | 2022 |
| Předmět: |
Captopril
Interleukin-6 Tumor Necrosis Factor-alpha Health Toxicology and Mutagenesis Angiotensin II Endothelial Cells Pulmonary Edema General Medicine Lung Injury Toxicology Biochemistry Antioxidants Etanercept Mice Occludin Necroptosis Molecular Medicine Animals Humans Reactive Oxygen Species Molecular Biology Lactate Dehydrogenases Cadmium Melatonin |
| Zdroj: | Journal of biochemical and molecular toxicologyREFERENCES. 36(10) |
| ISSN: | 1099-0461 |
| Popis: | The renin-angiotensin system (RAS) is an important regulator in pulmonary physiology. In our study, we identified the efficacy of melatonin to control the RAS in cadmium (Cd) induced chronic lung injury in a mouse model. Swiss albino mice exposed to CdCl |
| Databáze: | OpenAIRE |
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