Detection of Chlamydia trachomatis antigens by enzyme immunoassay and immunofluorescence in genital specimens from symptomatic and asymptomatic men and women
| Autor: | Stephen J. Landis, Iain O. Stewart, Everett J. Sargeant, Christine Leman, Santina Castriciano, Max Chernesky, William Seidelman, James B. Mahony, Maureen Mores |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Male medicine.medical_specialty Fluorescent Antibody Technique Chlamydia trachomatis Cervix Uteri medicine.disease_cause Asymptomatic Immunoenzyme Techniques Urethra parasitic diseases medicine Immunology and Allergy Humans Chlamydiaceae Sex organ Urethritis Cells Cultured Gynecology Antigens Bacterial biology medicine.diagnostic_test business.industry Chlamydia Infections bacterial infections and mycoses biology.organism_classification medicine.disease Uterine Cervicitis Infectious Diseases medicine.anatomical_structure Immunoassay Chlamydiales Female medicine.symptom business |
| Zdroj: | The Journal of infectious diseases. 154(1) |
| ISSN: | 0022-1899 |
| Popis: | Chlamydia trachomatis antigens were detected in populations with the following infection prevalences: 26.5% (36 of 136) of men and 27.7% (48 of 173) of women attending a sexually transmitted disease clinic, 16.3% (53 of 324) of women attending a Planned Parenthood clinic, and 3.4% (4 of 117) of an obstetrics and gynecologic practice. Compared with cell culture of the combined female cervical specimens (15.8% prevalence), the respective sensitivities of Chlamydiazyme (Abbott Laboratories, North Chicago, Illinois) and Microtrak (Syva, Palo Alto, California) were 98.3% and 87.9%, specificities were 97.5% and 98.4%, positive predictive values were 87.7% and 92.7%, and negative predictive values were 99.7% and 97.5%. Both assays were 70.0% sensitive with male urethral specimens, and the other parameters of performance ranged between 84.0% and 97.2%. The antigen detection assays, compared with culture, performed equally well in subjects without or with clinical signs. |
| Databáze: | OpenAIRE |
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