Changes in white blood cells during parturition in mothers and newborn
| Autor: | Reinhard Neubert, Isabella Delgado, Joachim W. Dudenhausen |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Lymphocyte Flow cytometry Blood cell Andrology Leukocyte Count Pregnancy Stress Physiological Medicine Humans Leukocytosis Lymphocyte Count Pathological Labor Obstetric medicine.diagnostic_test business.industry Cesarean Section Infant Newborn Obstetrics and Gynecology Venous blood medicine.disease Lymphocyte Subsets White (mutation) medicine.anatomical_structure Reproductive Medicine Immunology Female medicine.symptom business |
| Zdroj: | Gynecologic and obstetric investigation. 38(4) |
| ISSN: | 0378-7346 |
| Popis: | Following spontaneous delivery (n = 12) a pronounced increase in the maternal total white blood cell count was found (to [mean +/- SD]: 20 +/- 6 x 10(9) total leukocytes/l), which would be considered highly 'pathological' in nonpregnant women. The alteration was predominantly due to an increase in polymorphnuclear cells and band forms. Simultaneously, a drastic decrease in the percentage and the absolute number of lymphocytes was noticed in venous blood (from 32 to 5%, or [mean +/- SD]: from 2.7 +/- 0.7 to 1.1 +/- 0.3 x 10(9) total lymphocytes/l). In this decrease nearly all lymphocyte subtypes were involved, although to differing extents. Following elective caesarean delivery (n = 6), no leukocytosis was found, however the percentage and absolute number of lymphocytes was also decreased, although not as pronounced as after spontaneous delivery. Again not all the lymphocyte subpopulations were affected to the same degree, and the effect was especially obvious for the suppressor T cells and B cells. Following emergency caesarean delivery (n = 5), no obvious effect on the absolute number of lymphocytes or on the pattern of lymphocyte subpopulations was observed. However, the total number of white blood cells was clearly increased, as after spontaneous deliveries. The possible significance of these findings, also for therapeutic consequences during the perinatal period, is discussed. |
| Databáze: | OpenAIRE |
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