The Natural History of Upper Gastrointestinal Subepithelial Tumors
| Autor: | Rita Conigliaro, Lorenzo Camellini, Francesco Azzolini, Laith H. Jamil, Alessandro Messerotti, Micheal B. Wallace, Romano Sassatelli, Massimo Raimondo, Kanwar R. Gill, Timothy A. Woodward |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Endoscopic ultrasound medicine.medical_specialty Gastrointestinal Stromal Tumors Biopsy Fine-Needle Endoscopic ultrasonography Gastroenterology Endosonography Upper Gastrointestinal Tract Internal medicine Biopsy medicine Humans Upper gastrointestinal Aged Gastrointestinal Neoplasms Gastrointestinal endoscopy Natural course medicine.diagnostic_test business.industry Carcinoma Ultrasound Middle Aged digestive system diseases Natural history Female Radiology business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0192-0790 |
| Popis: | To evaluate the natural course of3-cm upper gastrointestinal subepithelial tumors by endoscopic ultrasound (EUS) and to determine the appropriate timing for EUS follow-up.Subepithelial tumors (SETs) can range from benign lesions to tumors with malignant behavior or potential to become malignant such as gastrointestinal stromal tumors (GISTs). EUS is considered a valuable tool for their evaluation as it estimates the exact size and layer of origin, and also additional morphologic features that can suggest the diagnosis. For high surgical risk patients and when no worrisome EUS features are seen, EUS surveillance of subepithelial tumors is often used.Fifty-one patients (mean age, 61.2+/-11.8 y; median, 63 y) with asymptomatic3-cm SETs of second and fourth echolayer were followed for a mean period of 29.7 months (range, 3 to 84; median, 23 mo) in 3 tertiary care institutions. Evaluation included location, echolayer, tumor diameter, internal echo pattern, and outer margin of lesions by EUS. EUS was performed by using miniprobes, radial and linear echoendoscopes.Follow-up revealed increase in size and/or change in echogenic features in 7/51 (13.7%) patients. Surgical follow-up was available for 3 of 7 of these patients. Two of the fourth layer SETs, which had both increase in size and change in echogenicity were found to be GISTs (+c-kit).The majority of3-cm SETs does not change during a median of 23 months. The change in echogenicity and increase in size may indicate a GIST. |
| Databáze: | OpenAIRE |
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