THE EFFECT OF THE REFERRING DIALYSIS CENTER ON RENAL TRANSPLANT RESULTS
Autor: | T. Quinn, Robert Soberman, Frank J. Veith, Arthur J. Matas, Vivian A. Tellis, Daniel Glicklich |
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Rok vydání: | 1988 |
Předmět: |
Adult
Resuscitation medicine.medical_specialty Referral medicine.medical_treatment Cyclosporins Azathioprine Ambulatory Care Facilities HLA Antigens Renal Dialysis Renin medicine Humans Blood Transfusion Dialysis Transplantation Kidney business.industry Graft Survival Immunosuppression Kidney Transplantation Surgery surgical procedures operative medicine.anatomical_structure Kidney Failure Chronic Prednisone Hemodialysis business medicine.drug |
Zdroj: | Transplantation. 45:894-898 |
ISSN: | 0041-1337 |
DOI: | 10.1097/00007890-198805000-00010 |
Popis: | Between 1/1/76 and 12/31/86, 448 patients underwent transplantation (360 first transplants). Of these, 286 (230 first) were referred by 5 dialysis centers, each referring more than 40 recipients. The remainder were referred by a large number of centers. Using our 5 largest referral centers, we studied the effect of dialysis center on graft and patient survival. There was no difference between dialysis centers in patient survival. Actuarial graft survival differed significantly for all cadaver transplants and for first cadaver transplants (P less than 105). Significant differences persisted when groups were subdivided by type of immunosuppression (azathioprine vs cyclosporine). Demographic (age, race, cause of renal disease) and immunologic (transfusions, PRA, matching) differences between groups did not explain the difference in graft survival. We conclude that referring dialysis center is a previously unrecognized factor affecting transplant outcome. Further studies with larger numbers will be required to determine the underlying reasons for ths phenomenon. |
Databáze: | OpenAIRE |
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