Primary Pulmonary Synovial Sarcoma Showing a Prolonged Survival with Multimodality Therapy
| Autor: | Taito Yamago, Masaki Hanibuchi, Yuko Toyoda, Yoshimi Bando, Shoji Sakiyama, Hirokazu Ogino, Hitoshi Ikushima, Seiji Iwamoto, Kohei Nakajima, Hiromitsu Takizawa, Hiroyuki Sumitomo, Shinji Nagahiro, Yasuhiko Nishioka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Thoracic Surgical Procedure Oncogene Proteins Fusion medicine.medical_treatment multimodality therapy Multimodality Therapy spontaneous regression Sarcoma Synovial 03 medical and health sciences 0302 clinical medicine Internal Medicine Humans Medicine brain metastasis primary pulmonary synovial sarcoma Brain Neoplasms business.industry Thoracic cavity DNA Neoplasm General Medicine Middle Aged Thoracic Surgical Procedures medicine.disease Combined Modality Therapy Synovial sarcoma Surgery Radiation therapy Treatment Outcome medicine.anatomical_structure 030228 respiratory system Cardiothoracic surgery 030220 oncology & carcinogenesis Sarcoma Radiology Neoplasm Recurrence Local business Brain metastasis |
| Zdroj: | Internal Medicine. 55(4):381-387 |
| ISSN: | 1349-7235 |
| Popis: | A 54-year-old man was referred to our hospital due to a mass shadow noted on a chest X-ray. Thoracoscopic lobectomy yielded a diagnosis of primary pulmonary synovial sarcoma according to the histology and SYT-SSX1 gene analyses. Five months after the thoracic surgery, he developed brain metastasis; therefore, we performed resection of the brain metastatic focus followed by radiotherapy. As a local recurrence in the thoracic cavity concurrently emerged, systemic chemotherapy was also administered. These observations indicated that a multidisciplinary approach may be useful against primary pulmonary synovial sarcoma, although there is presently no established therapeutic strategy due to its rarity and highly aggressive nature. |
| Databáze: | OpenAIRE |
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