Pelvic Exenteration: Experience from a Rural Cancer Center in Developing World
| Autor: | Atanu Bhattacharjee, Syam Vikram, Sampada Dessai, Santam Chakraborty, Satheesan Balasubramanian, Vijay Patil |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Article Subject Hospitals Rural medicine.medical_treatment India Cancer Care Facilities lcsh:RC254-282 Postoperative Complications Blood loss Surgical oncology medicine Overall survival Humans Progression-free survival Developing Countries Survival analysis Aged Pelvic Neoplasms Retrospective Studies Medical Audit Pelvic exenteration business.industry Cancer Middle Aged lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Survival Analysis Pelvic Exenteration Surgery Treatment Outcome Oncology Clinical Study Female business Limited resources Follow-Up Studies |
| Zdroj: | International Journal of Surgical Oncology, Vol 2015 (2015) International Journal of Surgical Oncology |
| ISSN: | 2090-1410 2090-1402 |
| Popis: | Background. Pelvic exenteration (PE) is a morbid procedure. Ours is a rural based cancer center limited trained surgical oncology staff. Hence, this audit was planned to evaluate morbidity and outcomes of all patients undergoing PE at our center.Methods. This is a IRB approved retrospective audit of all patients who underwent PE at our center from January 2010 to August 2013. The toxicity grades were retrospectively assigned according to the CTCAE version 4.02 criteria. Chi-square test was done to identify factors affecting grades 3–5 morbidity. Kaplan Meier survival analysis has been used for estimation of median PFS and OS.Results. 34 patients were identified, with the median age of 52 years (28–73 years). Total, anterior, posterior, and modified posterior exenterations were performed in 4 (11.8%), 5 (14.7%), 14 (41.2%), and 11 (32.4%) patients, respectively. The median time for surgery was 5.5 hours (3–8 hours). The median blood loss was 500 mL (200–4000 mL). CTCAE version 4.02 grades 3-4 toxicity was seen in nine patients (25.7%). The median estimated progression free survival was 31.76 months (25.13–38.40 months). The 2-year overall survival was 97.14%.Conclusion. PE related grades 3–5 morbidity of 25.7% and mortality of 2.9% at our resource limited center are encouraging. |
| Databáze: | OpenAIRE |
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