Genetic variation in the capsid region of human astrovirus serotype 4 isolated in Japan
| Autor: | Mihoko Matsui, Mitsuaki Oseto, Hiroshi Ushijima, Mussa Sanogo, Masahiko Hachiya, Keiichi Morooka |
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| Rok vydání: | 1999 |
| Předmět: |
Serotype
Antigenicity Immunology Molecular Sequence Data Microbiology Astrovirus Immunoenzyme Techniques Capsid Virology Genetic variation Genotype Humans Serotyping Phylogeny Genetics Molecular epidemiology biology Reverse Transcriptase Polymerase Chain Reaction Nucleic acid sequence Genetic Variation Sequence Analysis DNA biology.organism_classification RNA Viral Sequence Alignment Mamastrovirus |
| Zdroj: | Microbiology and immunology. 43(11) |
| ISSN: | 0385-5600 |
| Popis: | The entire capsid regions of 12 serotype-4 astroviruses from Japan were sequenced and compared with those of other serotypes. Serotype-4 isolates were divided into two new subgroups. The intrasubgroup nucleic acid and deduced amino acid sequences were quite homologous (more than 93%), but slightly less so between subgroups (almost 85%). However, the serotype-4 sequences differed from those of serotypes 1, 2, 3, 5, 6, 7 and 8 (less than 50%). Determining whether these differences significantly alter the epidemiology and antigenicity will require further investigation. |
| Databáze: | OpenAIRE |
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