ANALYSIS OF PROGNOSTIC FACTORS IN PATIENTS WITH GASTRIC VARICES AFTER ENDOSCOPIC TREATMENT
| Autor: | Hideo Shishido, Atsushi Irisawa, Takuto Hikichi, Hidemichi Imamura, Hiroaki Sakamoto, Reiji Kasukawa, Goro Shibukawa, Ayako Saito, Katsutoshi Obara, Tadayuki Takagi, Takeru Wakatsuki, Hiromasa Ohira, Ai Sato, Masaki Sato, Hitoshi Oyama, Yuta Takahashi, Fujio Takiguchi, Toshimitu Kuwana, Go Yamamoto |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis Oleic Acids Esophageal and Gastric Varices Gastroenterology Cohort Studies Recurrence Risk Factors Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Cyanoacrylates Aged Retrospective Studies medicine.diagnostic_test business.industry Endoscopy Retrospective cohort study Middle Aged Gastric varices medicine.disease Sclerosing Solutions Surgery Treatment Outcome Hemostasis Hepatocellular carcinoma Female Gastrointestinal Hemorrhage business Endoscopic treatment Cohort study |
| Zdroj: | Digestive Endoscopy. 21:232-238 |
| ISSN: | 1443-1661 0915-5635 |
| DOI: | 10.1111/j.1443-1661.2009.00898.x |
| Popis: | Background: The prognostic factors, including gastric variceal bleeding itself, in patients with gastric varices (GV) after endoscopic treatment remain unclear. The aim of this study was to analyze prognostic factors in patients with GV after endoscopic treatment as well as to evaluate safety and efficacy of our endoscopic treatment. Patients and Methods: This study enrolled 115 patients who underwent endoscopic treatment for GV between October 1988 and December 2003 using cyanoacrylate and 5% ethanolamine oleate. Successful hemostasis, recurrence rates, rebleeding rates, survival rates, complications and prognostic factors after the treatment were retrospectively reviewed. Results: Treatment sessions for GV were performed 3.4 ± 2.5 times. All cases, including 14 emergency cases, were treated successfully. The cumulative recurrence rates at 1, 3 and 5 years after the treatment were 7.0%, 15.6% and 20.0%, respectively, and the cumulative rebleeding rates at 1, 3 and 5 years were 3.5%, 8.7% and 14.8%, respectively. The overall survival rates were 78.3%, 63.7% and 51.5% at 1, 3 and 5 years, respectively. Grade B or C in Child–Pugh classification, emergency or elective cases, and association with hepatocellular carcinoma were identified as significant negative prognostic factors after endoscopic treatment by multivariate analysis. Although several complications were observed, there was no mortality. Conclusions: Grade B or C in Child–Pugh classification, emergency or elective situation, and association with hepatocellular carcinoma are negative prognostic factors after endoscopic treatment. |
| Databáze: | OpenAIRE |
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