Is overactive bladder microvasculature disease a component of systemic atheroscleorosis?
| Autor: | Reci Meseri, Ismail Mete Itil, Ahmet Özgür Yeniel, Ahmet Mete Ergenoglu, Handan Ak, Anıl Ari, Erkan Kismali, Hikmet Hakan Aydin, Sevcan Atay, Gulgun Kavukcu |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Urology Urinary system 030232 urology & nephrology Femoral artery urologic and male genital diseases Carotid Intima-Media Thickness 03 medical and health sciences 0302 clinical medicine medicine.artery medicine Humans Aged Ultrasonography Framingham Risk Score Urinary Bladder Overactive business.industry Middle Aged Atherosclerosis medicine.disease humanities female genital diseases and pregnancy complications Neck of urinary bladder Overactive bladder Case-Control Studies 030220 oncology & carcinogenesis Microvessels Cohort Mann–Whitney U test Female Neurology (clinical) business Perfusion |
| Zdroj: | ResearcherID |
| ISSN: | 1520-6777 0733-2467 |
| DOI: | 10.1002/nau.23452 |
| Popis: | Aims To evaluate the relationship between overactive bladder (OAB) and systemic atherosclerosis in a cohort of women. Methods In this case-control study, we assessed atherosclerosis indicators, such as Framingham risk scores and carotid and femoral artery intima-media thickness, and evaluated possible bladder wall responses to atherosclerosis using endovaginal color Doppler ultrasound and the detection of urinary cytokines in women with OAB and in controls. Quantitative assessment of blood perfusion at the bladder neck was performed using a method that allows for the dynamic monitoring of flow in a predefined region of interest at every point of the cardiac cycle. The independent samples t-test was used to evaluate the relationship between OAB and the atherosclerotic findings when parametric conditions were met, and the Mann-Whitney U test was used when parametric conditions were not met. Kendall's Tau was used to assess the correlation between OAB severity and the atherosclerotic variables. P |
| Databáze: | OpenAIRE |
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