Prospective longitudinal outcomes of quality of life after laparoscopic radical prostatectomy compared with retropubic radical prostatectomy

Autor: Iku Ninomiya, Toshio Kakuda, Katsuyoshi Hashine, Tadanori Hosokawa, Shunsuke Iuchi
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
medicine.medical_specialty
Multivariate analysis
Urinary function
Laparoscopic radical prostatectomy
Urinary system
medicine.medical_treatment
Health-related quality of life
030232 urology & nephrology
Urology
Urinary incontinence
lcsh:Computer applications to medicine. Medical informatics
03 medical and health sciences
Urinary bother
0302 clinical medicine
Quality of life
Medicine
Humans
Longitudinal Studies
Prospective Studies
Aged
Prostatectomy
Chi-Square Distribution
business.industry
Research
Public Health
Environmental and Occupational Health
Prostatic Neoplasms
General Medicine
Middle Aged
Urinary Incontinence
030220 oncology & carcinogenesis
Quality of Life
lcsh:R858-859.7
International Prostate Symptom Score
lipids (amino acids
peptides
and proteins)
Laparoscopy
medicine.symptom
business
Sexual function
Zdroj: Health and Quality of Life Outcomes
Health and Quality of Life Outcomes, Vol 16, Iss 1, Pp 1-8 (2018)
ISSN: 1477-7525
Popis: Background There have been few reports on health-related quality of life (HRQOL) after laparoscopic radical prostatectomy (LRP) in Japanese patients. The aim of this study is to assess changes in HRQOL during 36 months after LRP compared with retropubic radical prostatectomy (RRP). Methods The subjects were 105 consecutive patients treated with LRP between 2011 and 2012. HRQOL was evaluated using the International Prostate Symptom Score (IPSS), Medical Outcome Study 8-Items Short Form Health Survey (SF-8), and Expanded Prostate Cancer Index Composite (EPIC) at baseline and 1, 3, 6, 12 and 36 months after surgery. These results were compared with data for 107 consecutive patients treated with RRP between 2005 and 2007. The comparison between LRP and RRP was examined at every time point by Mann-Whitney U-test and chi-square test. Multiple linear regression analysis was used to identify independent factors related to the urinary domain in EPIC. Results The IPSS change was similar in both groups. The LRP group had a better SF-8 mental component summary score at baseline and a better SF-8 physical component summary score at 1 month after surgery. In EPIC, urinary function and bother were worse after LRP, but improved at 12 months and did not differ significantly from those after RRP; however, these factors then worsened again at 36 months after LRP. Urinary incontinence was also worse at 36 months after LRP, compared to RRP. In patients treated with nerve-sparing surgery, urinary function and urinary incontinence were similar and good at 12 and 36 months in both groups. Bowel function and bother, and sexual function and bother were similar in both groups and showed no changes from 12 to 36 months. Age and salvage radiotherapy were independent predictors of incontinence (daily use of two or more pads) in multivariate analysis. Surgical procedure was not an independent factor for incontinence, but incontinence defined as use of one pad or more was associated with the surgical procedure. Conclusions Urinary function and bother at 36 months were worse after LRP than after RRP. Age, salvage radiotherapy and surgical procedure were associated with urinary incontinence after 36 months.
Databáze: OpenAIRE
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