Non-invasive analysis of skin mechanical properties in patients with lamellar ichthyosis
| Autor: | Maykel González-Torres, Jonathan J. Magaña, Noé Zacaula‐Juárez, Manuel González-Del Carmen, María C. León‐Trejo, Octavio D Reyes-Hernández, Wendy Diaz‐Beltran, Lizbeth Cariño‐Calvo, Hernán Cortés, Gerardo Leyva-Gómez |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Erythema Adolescent Dermatology 01 natural sciences 010309 optics 030207 dermatology & venereal diseases 03 medical and health sciences Young Adult 0302 clinical medicine Skin Physiological Phenomena 0103 physical sciences medicine Humans In patient Child Aged Skin business.industry Ichthyosis Non invasive Infant Lamellar ichthyosis Middle Aged medicine.disease Elasticity Biomechanical Phenomena Child Preschool Female medicine.symptom business Ichthyosis Lamellar |
| Zdroj: | Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 25(3) |
| ISSN: | 1600-0846 |
| Popis: | Background Reliable methods for the quantitative evaluation of skin of patients with ichthyosis are critically needed. Our purpose was to evaluate the biomechanical parameters of skin in a cohort of patients with clinically diagnosed lamellar ichthyosis. Materials and methods Twenty-two patients diagnosed with lamellar ichthyosis were studied. Ichthyosis plaques located in upper distal limbs were assayed, and a nearby anatomical region without plaques from the same patient was employed as control. Skin biomechanical properties were studied through a non-invasive device (Cutometer® MPA 580). Results Ichthyosis plaques had higher values for the Uf-Ua parameter and lower values for the Ua/Uf, Ur/Ue, and Ur/Uf parameters. Adults and children showed similar statistical differences. There were no significant differences in data from men, whereas in women differences for all of the parameters were found. There was a significant decrease in the hydration and an increase in melanin index in the ichthyosis plaques. Conclusion Our results suggest that analysis of parameters Uf-Ua, Ua/Uf, Ur/Ue, Ur/Uf, hydration, and melanin index could be employed for quantitative monitoring of skin. Therefore, the non-invasive method applied may be suitable for evaluation of skin of patients with ichthyosis in response to medical treatments. |
| Databáze: | OpenAIRE |
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