Association of CT perfusion imaging with plasma levels of TGF-β1 and VEGF in patients with NSCLC
| Autor: | Yu-Sen Shi, Bao-Zhong Wu, Zhi-Qun Li, Da-Wei Li, Xiao-Hua Li, Xu-Dong Liu |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Blood volume Perfusion scanning 03 medical and health sciences 0302 clinical medicine medicine In patient Lung cancer Medicine(all) business.industry Vascular endothelial growth General Medicine Plasma levels Blood flow medicine.disease 030104 developmental biology 030220 oncology & carcinogenesis Non small cell lung cancer Transforming growth factor-β1 Nuclear medicine business Perfusion CT perfusion parameters Transforming growth factor |
| Zdroj: | Asian Pacific Journal of Tropical Medicine. 9:177-179 |
| ISSN: | 1995-7645 |
| Popis: | ObjectiveTo study the association of CT perfusion imaging parameters with plasma level of transforming growth factor-β1 (TGF-β1) and vascular endothelial growth (VEGF) in patients with non small cell lung cancer (NSCLC).MethodsA total of 67 patients with NSCLC (NSCLC group) and 64 patients with benign lesion (control group) were given with CT perfusion imaging to obtain blood flow, blood volume, mean transit time, time to peal and permeability surface through CT perfusion software. The plasma levels of TGF-β1 and VEGF were tested by ELISA. The relationship between plasma levels of TGF-β1, VEGF and CT perfusion imaging parameters were analyzed.ResultsCT perfusion imaging parameters and the plasma levels of TGF-β1 and VEGF of NSCLC group were significantly higher than the control group (P |
| Databáze: | OpenAIRE |
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