Intralesional measles, mumps, and rubella vaccine immunotherapy in molluscum contagiosum: A retrospective observational study from a tertiary care center in north India
| Autor: | Dilip Meena, Rashmi Jindal, Payal Chauhan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Molluscum Contagiosum Adolescent Mucocutaneous zone India Dermatology Injections Intralesional MMR vaccine Measles Rubella Tertiary Care Centers 030207 dermatology & venereal diseases 03 medical and health sciences Rubella vaccine Young Adult 0302 clinical medicine Medicine Humans Adverse effect Child Retrospective Studies Molluscum contagiosum business.industry Retrospective cohort study General Medicine Middle Aged medicine.disease 030220 oncology & carcinogenesis Female Immunotherapy business Measles-Mumps-Rubella Vaccine medicine.drug |
| Zdroj: | Dermatologic therapyREFERENCES. 34(1) |
| ISSN: | 1529-8019 |
| Popis: | Molluscum contagiosum (MC) is a mucocutaneous viral infection, often self-limiting but untreated lesions can often last for 2 months to 2 years. Previously intralesional measles, mumps, and rubella (MMR) vaccine has been tried for the treatment of warts but no studies exist of its use in MC. We report our experience with intralesional MMR in 22 patients of MC. The study was carried out to assess the efficacy and safety of intralesional MMR vaccine in patients of MC. We retrospectively analyzed records of patients who received intralesional MMR for MC from September 2018 to September 2019. Demographic characteristics, number, size, and site of molluscum lesions, number of MMR injections given, and response were recorded. Records of 22 patients were analyzed. There were 10 males and 12 females. The age of the patients ranged from 6 to 50 years with a mean of 19.72 ± 10.92. At the end of 12 weeks, 18 patients (81.8%) had complete clearance of lesions, with 4 patients (18.18%) having a partial response of more than 50%. No patient showed less than 50% or no response. In only one patient who had giant molluscum, postinflammatory hyperpigmentation was noted. No other adverse effect was seen in any of the patients. MMR is a safe, effective, easy to administer, time-saving, and inexpensive therapy for lesions of MC. |
| Databáze: | OpenAIRE |
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