Metabolic-associated fatty liver disease is associated with low muscle mass and strength in patients with chronic hepatitis B

Autor: Cecy Maria de Lima, Santos, Matheus Duarte, Brito, Pedro Alves Soares Vaz, de Castro, Thais Pontello, de Vries, Nataly Lopes, Viana, Marta Paula Pereira, Coelho, Olívio Brito, Malheiro, Tatiana, Bering, Maria Cristina, Gonzalez, Rosângela, Teixeira, Rodrigo Dias, Cambraia, Gifone Aguiar, Rocha, Luciana Diniz, Silva
Rok vydání: 2022
Předmět:
Zdroj: World Journal of Hepatology. 14:1652-1666
ISSN: 1948-5182
Popis: Although the prognostic relevance of sarcopenia has been increasingly recognised in the context of liver disease, there is a paucity of data evaluating body composition in patients with chronic hepatitis B (CHB). Beyond virus-related factors, nutritional and metabolic aspects can be associated with skeletal muscle abnormalities in these patients and should not be disregarded.To evaluate the association between components of sarcopenia and demographic, clinical, lifestyle, nutritional, and biochemical variables in CHB patients.Dual-energy X-ray absorptiometry (DXA) was used to assess muscle mass by quantifying appendicular lean mass (ALM) adjusted for body mass index (ALMThis cross-sectional study included 105 CHB outpatients followed at the tertiary care ambulatory centre (mean age, 48.5 ± 12.0 years; 58.1% males; 76.2% without cirrhosis; 23.8% with compensated cirrhosis). The DXA-derived fat mass percentage was inversely correlated with the ALMMAFLD and central obesity were associated with low muscle mass and strength in patients with chronic hepatitis B, independent of the liver disease stage.
Databáze: OpenAIRE