Asymmetric Synthesis of Antithrombotic Agents M58163 and M58169: Dynamic Kinetic Resolution in Amide Formation Catalyzed by La-Linked BINOL Complex

Autor:	Takafumi Mukaihira, Hidemitsu Nishida, Fumihiko Saitoh, Kohsuke Aikawa, Koichi Mikami
Rok vydání:	2006
Předmět:	chemistry.chemical_compound Antithrombotic Agent Chemistry Stereochemistry Amide Organic Chemistry Antithrombotic Enantioselective synthesis General Medicine Physical and Theoretical Chemistry Combinatorial chemistry Catalysis Kinetic resolution
Zdroj:	European Journal of Organic Chemistry. 2006:5454-5457
ISSN:	1099-0690 1434-193X
DOI:	10.1002/ejoc.200600838
Popis:	The first asymmetric syntheses of antithrombotic agents M58163 and M58169 are reported. Dynamic kinetic resolution is observed in the amide formation step. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Databáze:	OpenAIRE
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