Pediatric Experience With the VentrAssist LVAD
| Autor: | Justin Negri, Alastair McGeorge, H. Gibbs, Shay McGuinness, Don Esmore, Kirsten Finucane, Peter Ruygrok, Kylie Jones, Peter Alison |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Cardiomyopathy
Dilated Male Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent medicine.medical_treatment Cardiomyopathy Ventricular Dysfunction Left Fatal Outcome medicine Humans Child Heart Failure Heart transplantation business.industry Continuous flow Equipment Design medicine.disease Combined Modality Therapy Surgery Clinical trial Donor heart El Niño Ventricular assist device Heart failure Heart Transplantation Female Heart-Assist Devices Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Annals of Thoracic Surgery. 86:622-626 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/j.athoracsur.2008.03.009 |
| Popis: | Purpose The purpose of this study is to describe the first experience of implanting a new left ventricular assist device in pediatric patients with end-stage heart failure. Description In two recent prospective, international, multicenter clinical trials, three children (aged ≤ 16 years) were implanted successfully with the VentrAssist (Ventracor Limited, Chatswood, Australia), a relatively small, novel, continuous flow, third-generation left ventricular assist device. Evaluation Despite the patients' disease severity (each child was in extremis at the time of implantation), VentrAssist (Ventracor Limited) implantation enabled each patient to be discharged home from the hospital. All patients survived for more than 1 year. One patient was successfully transplanted and another was bridged to an adequate degree of recovery; unfortunately, the third patient died on postoperative day 375 while waiting for a suitable donor heart. Consistent with the complications associated with left ventricular assist devices in adults, the main complications in these pediatric patients were infection and thromboembolism. Conclusions The VentrAssist may provide a major advancement in the management of larger children and adolescents with end-stage heart failure. |
| Databáze: | OpenAIRE |
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