Postoperative analgesic efficacy of continuous wound infusion with local anesthetics after laparoscopy (PAIN): a randomized, double-blind, placebo-controlled trial
| Autor: | Nae Hyun Lee, Taejong Song, Kyoung-Ho Ryu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Laparoscopic surgery medicine.medical_treatment Analgesic Placebo-controlled study Placebo 03 medical and health sciences 0302 clinical medicine Double-Blind Method Humans Pain Management Medicine Prospective Studies Anesthetics Local Laparoscopy Pain Postoperative medicine.diagnostic_test business.industry Ropivacaine Surgical wound Analgesics Opioid Treatment Outcome 030220 oncology & carcinogenesis Anesthesia Female 030211 gastroenterology & hepatology Surgery business medicine.drug Abdominal surgery |
| Zdroj: | Surgical Endoscopy. 35:562-568 |
| ISSN: | 1432-2218 0930-2794 |
| DOI: | 10.1007/s00464-020-07416-8 |
| Popis: | To investigate the efficacy of continuous wound infusion (CWI) with local anesthetics for reducing postoperative pain compared with placebo in patients undergoing benign gynecologic laparoscopy. In this double-blind trial, 66 patients were randomly assigned to receive either ropivacaine or normal saline though a multi-orifice catheter placed into the umbilical surgical wound for 50 h postoperatively. The primary outcome measure was the severity of postoperative pain 1, 6, 12, 24, and 48 h after surgery. The secondary outcome measure was the number of rescue analgesics requested. Baseline characteristics did not statistically differ between the ropivacaine and placebo groups. The intensity of postoperative pain was significantly lower in the ropivacaine group than in the placebo group 1, 6, 12, 24, and 48 h after surgery (all P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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