Enzymes that hydrolyze adenine nucleotides in chronic renal failure: Relationship between hemostatic defects and renal failure severity
| Autor: | Rafael Fernandes Zanin, Luís C. Arantes, Vera Maria Morsch, Maria do Carmo Araújo, Maísa Corrêa, Maria Rosa Chitolina Schetinger, Adriane Cismoski da Silva, André L.B. Morsch |
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| Rok vydání: | 2005 |
| Předmět: |
Blood Platelets
medicine.medical_specialty Time Factors medicine.medical_treatment NTPDase 5'-nucleotidase Antigens CD Renal Dialysis Adenine nucleotide Internal medicine Chronic renal failure medicine Humans Urea Platelet 5'-Nucleotidase Molecular Biology chemistry.chemical_classification Analysis of Variance Apyrase Adenine Creatine Endocrinology Enzyme chemistry Hemodialysis Kidney Failure Chronic Molecular Medicine ATP diphosphohydrolase 5′-nucleotidase |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1741:282-288 |
| ISSN: | 0925-4439 |
| DOI: | 10.1016/j.bbadis.2005.06.002 |
| Popis: | The activities of the enzymes NTPDase (E.C.3.6.1.5, apyrase, ATP diphosphohydrolase, ecto-CD39) and 5′-nucleotidase (E.C.3.1.3.5, CD73) were analyzed in platelets from patients with chronic renal failure (CRF), both undergoing hemodialysis treatment (HD) and not undergoing hemodialysis (ND), as well as from a control group. The results showed an increase in platelet NTPDase activity in CRF patients on HD treatment (52.88%) with ATP as substrate (P |
| Databáze: | OpenAIRE |
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