Hepatitis E virus: A leading cause of waterborne viral hepatitis in Northwest Districts of Punjab, India
Autor: | Manpreet Kaur, Nachhatar Jit Singh, Kanwardeep Singh, Pushpa Devi, Maninder Kaur, Shailpreet K Sidhu |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Igm antibody viruses 030231 tropical medicine 030106 microbiology Prevalence lcsh:Medicine hepatitis E virus medicine.disease_cause Acute viral hepatitis 03 medical and health sciences 0302 clinical medicine Hepatitis E virus Environmental health hepatitis A virus medicine Diagnostic laboratory Hepatitis business.industry lcsh:R Outbreak virus diseases medicine.disease Virology Hepatitis a virus digestive system diseases outbreaks Original Article Viral hepatitis business |
Zdroj: | Journal of Laboratory Physicians Journal of Laboratory Physicians, Vol 9, Iss 02, Pp 121-124 (2017) |
ISSN: | 0974-2727 |
Popis: | BACKGROUND: Acute viral hepatitis (AVH) caused by enterically transmitted hepatitis A virus (HAV) and hepatitis E virus (HEV) poses a major health problem in developing countries such as India. Despite improving sanitation, heath awareness, and socioeconomic conditions, these infections continue to occur both in sporadic as well as in epidemic forms in different parts of India AIMS The aim of this study is to determine the total as well as age-specific prevalence rates of HAV and HEV in the outbreaks of waterborne hepatitis in districts surrounding Amritsar region of Punjab. MATERIALS AND METHODS: The study was conducted in the Virology Research and Diagnostic Laboratory, Government Medical College, Amritsar, during the study period of January 2015–March 2016. Samples from suspected outbreaks of AVH occurring in various districts around Amritsar were included as a part of the study. A total of 95 sera were tested for IgM antibody to HEV and HAV using IgM capture ELISA kit. RESULTS: Out of the total 95 samples received, 73 samples (76.84%) were positive for HAV/HEV. Out of the total positive cases, 65 (68.42%) had HEV infection, 2 (2.1%) had HAV, and 6 cases (6.31%) were coinfected with both HAV and HEV. The 21–30 years age group (25 cases) was identified as the most susceptible group for HEV infection. The coinfected subjects presented a wider range of age distribution (1–10 years: 1; 11–20 years: 3; 21–30 years: 1; 31–40 years: 1). Seasonal distribution of data revealed bimodal peaks for HEV infection. CONCLUSION: There should be some surveillance system to regularly monitor the portability of drinking water from time to time to avoid such preventable outbreaks in future. |
Databáze: | OpenAIRE |
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