MR and CT imaging characteristics and ablation zone volumetry of locally advanced pancreatic cancer treated with irreversible electroporation

Autor: Laurien G. P. H. Vroomen, Martijn R. Meijerink, Hester J. Scheffer, Janneke van den Bergh, Geert Kazemier, Marcus C. de Jong, Foke van Delft, Cornelis van Kuijk, Marleen C. A. M. Melenhorst
Přispěvatelé: Radiology and nuclear medicine, CCA - Imaging and biomarkers, AGEM - Re-generation and cancer of the digestive system, Other Research, Gastroenterology and hepatology, AGEM - Digestive immunity, Surgery
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Adult
Male
medicine.medical_specialty
Pancreatic neoplasms
medicine.medical_treatment
Ablation
Adenocarcinoma
Multimodal Imaging
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Tumour volume
medicine
Humans
Radiology
Nuclear Medicine and imaging
Computed tomography
Neuroradiology
Aged
medicine.diagnostic_test
business.industry
Ultrasound
fungi
Magnetic resonance imaging
Interventional radiology
General Medicine
Irreversible electroporation
Middle Aged
medicine.disease
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging
Electroporation
Treatment Outcome
Oncology
Radiology Nuclear Medicine and imaging
030220 oncology & carcinogenesis
Female
Radiology
Neoplasm Recurrence
Local
business
Nuclear medicine
Tomography
X-Ray Computed
Ablation zone
Zdroj: European Radiology
European Radiology, 27(6), 2521-2531. Springer Verlag
Vroomen, L G P H, Scheffer, H J, Melenhorst, M C A M, de Jong, M C, van den Bergh, J E, van Kuijk, C, van Delft, F, Kazemier, G & Meijerink, M R 2017, ' MR and CT imaging characteristics and ablation zone volumetry of locally advanced pancreatic cancer treated with irreversible electroporation ', European Radiology, vol. 27, no. 6, pp. 2521-2531 . https://doi.org/10.1007/s00330-016-4581-2
ISSN: 0938-7994
DOI: 10.1007/s00330-016-4581-2
Popis: Objectives To assess specific imaging characteristics after irreversible electroporation (IRE) for locally advanced pancreatic carcinoma (LAPC) with contrast-enhanced (ce)MRI and ceCT, and to explore the correlation of these characteristics with the development of recurrence. Methods Qualitative and quantitative analyses of imaging data were performed on 25 patients treated with percutaneous IRE for LAPC. Imaging characteristics of the ablation zone on ceCT and ceMRI were assessed over a 6-month follow-up period. Contrast ratio scores between pre- and post-treatment were compared. To detect early imaging markers for treatment failure, attenuation characteristics at 6 weeks were linked to the area of recurrence within 6 months. Results Post-IRE, diffusion-weighted imaging (DWI)-b800 signal intensities decreased in all cases (p
Databáze: OpenAIRE
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