Additional file 1 of Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS

Autor: Waters, Sarah, Swanson, Molly E. V., Dieriks, Birger V., Zhang, Yibin B., Grimsey, Natasha L., Murray, Helen C., Turner, Clinton, Waldvogel, Henry J., Faull, Richard L. M., An, Jiyan, Bowser, Robert, Curtis, Maurice A., Dragunow, Mike, Scotter, Emma
Rok vydání: 2021
DOI: 10.6084/m9.figshare.16456701
Popis: Additional file 1: Figure S1. Spinal cord transverse diameters. Figure S2. Immunogenicity of spinal cord was equivalent between DodgeTM and formalin fixation. Figure S3. Imaging and quantification workflow. Figure S4. Patterning of neither extravascular hemoglobin nor motor neuron pathology were affected by site of ALS onset; pTDP-43 inclusion load predicted motor neuron loss only in cervical cord of upper-limb onset cases. Figure S5. Extravascular hemoglobin did not correlate with motor neuron pathology, disease, or spinal cord tissue collection delay. Table S1. Review of blood-brain and blood-spinal cord barrier disruption in human ALS studies.
Databáze: OpenAIRE