Multiple Brown Tumors With Tc-99m MDP Superscan Appearance and Negative Tc-99m MIBI Uptake
| Autor: | Adonios Zanglis, Demetrios Andreopoulos, Athanassios Zissimopoulos, Nikolaos Baziotis |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Technetium Tc 99m Sestamibi musculoskeletal diseases Pathology medicine.medical_specialty Bone Neoplasms Technetium Tc 99m Medronate Lesion Biopsy medicine Humans Whole Body Imaging Radiology Nuclear Medicine and imaging Osteoblastoma Radionuclide Imaging False Negative Reactions Parathyroid adenoma Rib cage Hyperparathyroidism medicine.diagnostic_test business.industry General Medicine medicine.disease Brown tumor Giant cell Radiopharmaceuticals medicine.symptom business Nuclear medicine Hypophosphatemia |
| Zdroj: | Clinical Nuclear Medicine. 31:640-643 |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/01.rlu.0000237968.88074.fb |
| Popis: | A 20-year-old man presented with a spontaneous left humerus fracture after minimal loading. X-rays and a CT scan revealed multiple lytic lesions throughout the skeleton (humeri, ribs, spine, pelvic bones, femorals). Blood chemistries showed severe hypercalcemia of 15.7 mg/dL and hypophosphatemia, whereas the biopsy of a lytic lesion (right humerus) showed only a few macrophages and multinuclear giant cells. Tc-99m MDP and Tc-99m MIBI scans were performed. Neck surgery verified the presence of a parathyroid adenoma. The multiple lytic lesions that were seen are brown tumors (osteoclastomas) without focal Tc-99m MDP or Tc-99m MIBI uptake. |
| Databáze: | OpenAIRE |
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