The relation between age and time to maximal bronchoconstriction following exercise in children
| Autor: | Arie Augarten, Ori Efrati, Asher Barak, Amir Szeinberg, Yaacov Yahav, Daphna Vilozni |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Spirometry medicine.medical_specialty Time Factors Adolescent Exercise testing Bronchoconstriction Physical exercise Pulmonary function testing Internal medicine medicine Humans Child Retrospective Studies Asthma medicine.diagnostic_test Pediatric asthma business.industry Pulmonary function test Age Factors Retrospective cohort study medicine.disease Asthma Exercise-Induced El Niño Child Preschool Practice Guidelines as Topic Exercise Test Cardiology Physical therapy Female Airway obstruction medicine.symptom business Nadir (topography) circulatory and respiratory physiology |
| Zdroj: | Respiratory Medicine. 103:1456-1460 |
| ISSN: | 0954-6111 |
| DOI: | 10.1016/j.rmed.2009.04.028 |
| Popis: | SummaryBackgroundThe exercise challenge test (ECT) is a common tool for assessment of asthma in children. Many studies suggest that the “time to maximal bronchoconstriction” (Nadir-t) after exercise challenge in asthmatic children may be age-dependent, although this has never been systematically studied. Such findings may influence epidemiological surveys where the schedule of post-exercise measurements is trimmed. This study systematically assesses the relation between age and time to maximal bronchoconstriction post-ECT.MethodsData were collected retrospectively from 131 subjects (87 male; 3–18 years) who were referred for ECT. The routine ECT was performed according to ATS recommendation of a 6-min run. Spirometry was measured at 1, 3, 5, 10, 15, and 20min post-exercise. The post-exercise nadir of FEV1 (%baseline) (FEV1-nadir) and the time to maximal fall in Nadir-t (minutes) were sought and values were related to age.ResultsBaseline FEV1 values (mean±SD) were 90.5±13.8% predicted. FEV1-nadir was −23.6±11.7% from baseline values. The Nadir-t was reached at 5.1±2.6min (range 2–12min). A positive correlation between children's age and Nadir-t was observed (r2=0.542; SD of residuals=1.79; p |
| Databáze: | OpenAIRE |
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