Clinical and endoscopic presentation of primary gastric lymphoma: a multicentre study
| Autor: | Cesare Hassan, Mario Cottone, A Andriani, M. Vinci, George Bonanno, L Caruso, F. Di Raimondo, A. Mistretta, G. Lizzani, A. Zullo, C. Marrone, L. Tedeschi, L.M. Montalbano, C. Linea, A. Miedico, Michele Bibas, S. Morini, Antonio de Lisboa Lopes Costa, Caterina Patti, Annalisa Chiarenza, Salvo Mirto, Federico Stella, A. Romanelli, G. Restivo, U Recine |
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| Přispěvatelé: | ANDRIANI A, ZULLO A, DI RAIMONDO F, PATTI C, TEDESCHI L, RECINE U, CARUSO L, BONANNO G, CHIARENZA A, LIZZANI G, MIEDICO A, ROMANELLI A, COSTA A, LINEA C, MARRONE C, MIRTO S, MISTRETTA A, MONTALBANO L, RESTIVO G, VINCI M, BIBAS M, HASSAN C, STELLA F, COTTONE M, MORINI S |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Male
gastric lymphoma.helicobacter medicine.medical_specialty Lymphoma Settore MED/12 - GASTROENTEROLOGIA Gastroenterology Endoscopy Gastrointestinal Helicobacter Infections immune system diseases Stomach Neoplasms hemic and lymphatic diseases Internal medicine medicine Gastric mucosa Humans Pharmacology (medical) Antrum Neoplasm Staging Retrospective Studies Hepatology medicine.diagnostic_test biology Helicobacter pylori business.industry Gastric lymphoma Stomach Retrospective cohort study Middle Aged medicine.disease biology.organism_classification Endoscopy medicine.anatomical_structure Gastric Mucosa Female business |
| Popis: | 1. Aliment Pharmacol Ther. 2006 Mar 15;23(6):721-6. Clinical and endoscopic presentation of primary gastric lymphoma: a multicentre study. Andriani A, Zullo A, Di Raimondo F, Patti C, Tedeschi L, Recine U, Caruso L, Bonanno G, Chiarenza A, Lizzani G, Miedico A, Romanelli A, Costa A, Linea C, Marrone C, Mirto S, Mistretta A, Montalbano L, Restivo G, Vinci M, Bibas M, Hassan C, Stella F, Cottone M, Morini S. Department of Haematology and Gastroenterology, 'San Giacomo' and 'Nuovo Regina Margherita' Hospitals, Rome, Italy. BACKGROUND: Although the stomach is the most frequent site of intestinal lymphomas, few data are available on both clinical endoscopic presentation of gastric lymphoma and possible differences between low-grade and high-grade lymphomas. METHODS: Clinical, histological and endoscopic records of consecutive patients with primary low-grade or high-grade lymphoma diagnosed were retrieved. Symptoms were categorized as 'alarm' or 'not alarm'. The endoscopic findings were classified as 'normal' or 'abnormal'. RESULTS: Overall, 144 patients with primary gastric lymphoma were detected, including 74 low-grade and 70 high-grade lymphoma. Alarm symptoms, particularly persistent vomiting and weight loss, were more frequently present in patients with high-grade lymphoma than in those with low-grade lymphoma (54% vs. 28%; P = 0.002). Low-grade lymphomas presented as 'normal' appearing mucosa (20% vs. 0%; P = 0.0004) or petechial haemorrhage in the fundus (9% vs. 0%; P = 0.02) more frequently than high-grade lymphomas, being also more often confined to the antrum (47% vs. 27%, P = 0.03) and associated with Helicobacter pylori infection (88% vs. 52%, P < 0.0001). On the contrary, high-grade lymphomas presented more commonly as ulcerative type (70% vs. 52%; P = 0.03), being also more frequently diagnosed in stage >I when compared with low-grade lymphomas (70% vs. 21%, P < 0.0001). CONCLUSIONS: The overall prevalence of alarm symptoms is quite low and may be absent in more than 70% of patients with low-grade lymphoma. |
| Databáze: | OpenAIRE |
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