Plant Development Is Regulated by a Family of Auxin Receptor F Box Proteins
| Autor: | Masashi Yamada, Lawrence Hobbie, Nihal Dharmasiri, Gerd Jürgens, Jasmin S. Ehrismann, Esther Lechner, Dolf Weijers, Mark Estelle, Sunethra Dharmasiri |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
0106 biological sciences
Mutant Arabidopsis Receptors Cell Surface medicine.disease_cause 01 natural sciences F-box protein General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Auxin medicine heterocyclic compounds Receptor Molecular Biology Plant Proteins 030304 developmental biology chemistry.chemical_classification 0303 health sciences Mutation Indoleacetic Acids biology Arabidopsis Proteins F-Box Proteins fungi food and beverages Cell Biology Plants Genetically Modified biology.organism_classification Phenotype chemistry Biochemistry biology.protein Plant hormone Signal transduction Signal Transduction Transcription Factors 010606 plant biology & botany Developmental Biology |
| Zdroj: | Developmental Cell. 9(1):109-119 |
| ISSN: | 1534-5807 |
| DOI: | 10.1016/j.devcel.2005.05.014 |
| Popis: | SummaryThe plant hormone auxin has been implicated in virtually every aspect of plant growth and development. Auxin acts by promoting the degradation of transcriptional regulators called Aux/IAA proteins. Aux/IAA degradation requires TIR1, an F box protein that has been shown to function as an auxin receptor. However, loss of TIR1 has a modest effect on auxin response and plant development. Here we show that three additional F box proteins, called AFB1, 2, and 3, also regulate auxin response. Like TIR1, these proteins interact with the Aux/IAA proteins in an auxin-dependent manner. Plants that are deficient in all four proteins are auxin insensitive and exhibit a severe embryonic phenotype similar to the mp/arf5 and bdl/iaa12 mutants. Correspondingly, all TIR1/AFB proteins interact with BDL, and BDL is stabilized in triple mutant plants. Our results indicate that TIR1 and the AFB proteins collectively mediate auxin responses throughout plant development. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|