Vaccination of cattle against bovine viral diarrhoea

Autor: C. J. M. Bruschke, J.T. van Oirschot, P.A. van Rijn
Rok vydání: 1999
Předmět:
ID - Infectieziekten
Vaccine safety
Antigenic diversity
animal diseases
viruses
Vaccine efficacy
Vaccines
Attenuated
Microbiology
Virus
Flaviviridae
Fetus
Bovine virus diarrhoea
Congenital infection
Animals
Vaccines
Combined
Instituut voor Dierhouderij en Diergezondheid
Disease Reservoirs
Viral diarrhoea
Diarrhea Viruses
Bovine Viral
ID-Lelystad
General Veterinary
biology
Immunogenicity
Vaccination
Pestivirus
virus diseases
Viral Vaccines
General Medicine
biochemical phenomena
metabolism
and nutrition
biology.organism_classification
Virology
Virology & Molecular Biology
Virologie & Moleculaire Biologie
ID Lelystad
Vaccines
Inactivated
ID-Lelystad
Instituut voor Dierhouderij en Diergezondheid
ID Lelystad
Institute for Animal Science and Health
Immunology
Bovine Virus Diarrhea-Mucosal Disease
Cattle
Viral disease
Institute for Animal Science and Health
Zdroj: Veterinary Microbiology, 64(2-3), 169-183
Veterinary Microbiology 64 (1999) 2-3
ISSN: 0378-1135
DOI: 10.1016/s0378-1135(98)00268-5
Popis: This brief review describes types and quality (efficacy and safety) of bovine viral diarrhoea virus (BVDV) vaccines that are in the market or under development. Both conventional live and killed vaccines are available. The primary aim of vaccination is to prevent congenital infection, but the few vaccines tested are not highly efficacious in this respect, as shown in vaccination-challenge experiments. Vaccination to prevent severe postnatal infections may be indicated when virulent BVDV strains are prevalent. Live BVDV vaccines have given rise to safety problems. A complication for the development of BVDV vaccines is the wide antigenic diversity among wild-type BVDV. There is ample room for improvement of both the efficacy and safety of BVDV vaccines, and it may be expected that better vaccines, among which marker vaccines, will be launched in the future.
Databáze: OpenAIRE
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