The synergistic effect of tobacco and alcohol consumption on oral squamous cell carcinoma: a systematic review and meta-analysis
| Autor: | Fernanda Weber Mello, Elena Riet Correa Rivero, Carolina Amália Barcellos Silva, Saman Warnakulasuriya, Gilberto Melo, Júlia Jacoby Pasetto |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Tobacco
Smokeless Alcohol Drinking Population Alcohol Odds 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Risk Factors Environmental health Humans Medicine Prospective Studies education General Dentistry Retrospective Studies Mouth neoplasm education.field_of_study business.industry Smoking 030206 dentistry Odds ratio Confidence interval stomatognathic diseases Smokeless tobacco chemistry 030220 oncology & carcinogenesis Meta-analysis Carcinoma Squamous Cell Mouth Neoplasms business |
| Zdroj: | Clinical Oral Investigations. 23:2849-2859 |
| ISSN: | 1436-3771 1432-6981 |
| Popis: | This systematic review (SR) aimed to summarise and critically appraise available evidence about the association between the synergistic consumption of alcohol and tobacco and the occurrence of oral squamous cell carcinoma (OSCC). Observational studies investigating the association between the synergistic consumption of alcohol and tobacco and OSCC occurrence were included. Studies were selected in a two-phase process and searches were conducted on five main electronic databases, complemented by three grey literature databases. From 3260 records identified, 33 articles were included for qualitative analysis, of which 15 were included in the meta-analyses. Overall, the synergistic consumption was positively associated with the occurrence of OSCC (odds ratio [OR] = 5.37; 95% confidence interval [95%CI] = 3.54–8.14). Increased odds for OSCC occurrence were observed regarding the synergistic consumption of alcohol and smoked tobacco (OR = 4.74; 95%CI = 3.51–6.40), alcohol and smokeless tobacco (OR = 7.78; 95%CI = 2.86–21.14), and alcohol, smoked tobacco, and smokeless tobacco (OR = 16.17; 95%CI = 7.97–32.79). According to the results of this SR, the synergistic consumption of alcohol and tobacco (both smoked and smokeless) significantly increased the odds for the occurrence of OSCC. The knowledge provided by this SR may be useful for a better understanding of differences in the effect of synergistic consumption of alcohol and tobacco products in OSCC development. These data might aid healthcare authorities to develop measures for tobacco and alcohol control considering the needs of their population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink