Experimental evidence of increased ipsilateral gentamicin nephrotoxicity after unilateral ureteral obstruction
Autor: | Karafin L, A. Richard Kendall, David B. Lillie |
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Rok vydání: | 1981 |
Předmět: |
Male
Kidney medicine.medical_specialty urogenital system Experimental model business.industry Urology Aminoglycoside Inulin Renal function Acute Kidney Injury Kidney Function Tests urologic and male genital diseases Rats Nephrotoxicity medicine.anatomical_structure medicine Animals Gentamicin Gentamicins business Ureteral Obstruction medicine.drug |
Zdroj: | Urology. 17:249-251 |
ISSN: | 0090-4295 |
DOI: | 10.1016/0090-4295(81)90041-8 |
Popis: | This study describes an experimental model for the investigation of nephrotoxicity in which the aminoglycoside, gentamicin, is given after unilateral ureteral obstruction is produced. The preliminary findings indicate a significantly more severe loss of renal function in the obstructed kidney which receives gentamicin than in the obstructed kidney which does not. |
Databáze: | OpenAIRE |
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