Glycated Albumin Predicts Long-term Survival in Patients Undergoing Hemodialysis
| Autor: | Wen Ya Ma, Kuo Cheng Lu, Jia Fwu Shyu, Yuh Feng Lin, Chien Lin Lu, Yuan Hung Wang, Yueh Min Liu, Chia-Chao Wu |
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| Rok vydání: | 2015 |
| Předmět: |
Blood Glucose
Glycation End Products Advanced Male medicine.medical_specialty medicine.medical_treatment 030209 endocrinology & metabolism Subgroup analysis Kaplan-Meier Estimate 030204 cardiovascular system & hematology Gastroenterology 03 medical and health sciences 0302 clinical medicine Glycated albumin Renal Dialysis Internal medicine Long term survival medicine Risk of mortality Humans In patient Glycated Serum Albumin Serum Albumin Glycemic Aged Proportional Hazards Models hemodialysis business.industry General Medicine Middle Aged mortality Surgery Survival Rate Diabetes Mellitus Type 2 Female Hemodialysis Hemoglobin business Biomarkers Research Paper |
| Zdroj: | International Journal of Medical Sciences |
| ISSN: | 1449-1907 |
| Popis: | Background: In patients with advanced renal dysfunction undergoing maintenance hemodialysis, glycated albumin (GA) levels may be more representative of blood glucose levels than hemoglobin A1C levels. The aim of this study was to determine the predictive power of GA levels on long-term survival in hemodialysis patients. Methods: A total of 176 patients with a mean age of 68.2 years were enrolled. The median duration of follow-up was 51.0 months. Receiver-operating characteristic curve analysis was utilized to determine the optimal cutoff value. We examined the cumulative survival rate by Kaplan-Meier estimates and the influence of known survival factors with the multivariate Cox proportional-hazard regression model. Results: In the whole patient group, cumulative survival in the low GA group was better than in the high GA group (p=0.030), with more prominence in those aged |
| Databáze: | OpenAIRE |
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