Expanding the 18F-Radiochemical Space: Synthesis and Applications of 1,1-18F-Difluorinated Alkenes

Autor: Matthew Tredwell
Rok vydání: 2019
Předmět:
Zdroj: Synlett. 30:1371-1376
ISSN: 1437-2096
0936-5214
Popis: The synthesis of 18F-perfluorinated motifs from [18F]fluoride is a non-trivial undertaking as highlighted by the few methods and range of motifs that are known. In this Synpacts article we highlight our recent work on the synthesis and derivatization of 1,1-18F-difluoroalkenes to expand the accessible radiochemical space with fluorine-18.1 Introduction2 Overview of the Main Strategies to Access 18F-Perfluorinated Motifs with [18F]Fluoride3 1,1-18F-Difluoroalkenes4 Conclusion
Databáze: OpenAIRE