Transcriptional map of chromosome region 6q16→q21
| Autor: | Chiara Magnanini, E. Karayianni, G. M. Maniatis, V. Orphanos, Giuseppe Barbanti-Brodano, Massimo Negrini, D. H. Spathas, Cristina Morelli |
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| Rok vydání: | 1999 |
| Předmět: |
Genetic Markers
Genetics Transcription Genetic Tumor suppressor gene Chromosome Mapping Biology law.invention Mice Gene mapping law Transcription (biology) Chromosome regions Animals Humans Suppressor Chromosomes Human Pair 6 Genes Tumor Suppressor Chromosomes Artificial Yeast Molecular Biology Chromosome 22 Gene Genetics (clinical) |
| Zdroj: | Cytogenetic and Genome Research. 86:263-266 |
| ISSN: | 1424-859X 1424-8581 |
| DOI: | 10.1159/000015356 |
| Popis: | We present the transcription map of chromosome region 6q16→q21 by mapping fifteen known genes within this region. Five genes lay in the subregion containing a tumor suppressor gene, eight genes are located in the subregion harboring a senescence gene, and two genes are distal to the latter region. The precise location of the genes was obtained using a previously described translocation and deletion mouse/human hybrid panel. An even more accurate definition was possible for the genes spanning the senescence gene region, since a previously described YAC contig with its restriction map was available. From this transcription map it is possible to derive a large region of synteny with mouse chromosome 10. |
| Databáze: | OpenAIRE |
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