Predictors of disability in adolescents and young adults with acquired brain injury after the acute phase
Autor: | M S Worm, Jan Brink Valentin, Hysse B Forchhammer, Søren Paaske Johnsen, Susanne Wulff Svendsen, Jørgen Feldbæk Nielsen |
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Rok vydání: | 2021 |
Předmět: |
030506 rehabilitation
medicine.medical_specialty Adolescent glasgow outcome scale–extended Neuroscience (miscellaneous) Glasgow Outcome Scale Logistic regression Young Adult 03 medical and health sciences 0302 clinical medicine Developmental and Educational Psychology medicine Humans Disabled Persons Acquired brain injury Fatigue Neurorehabilitation Receiver operating characteristic rehabilitation needs business.industry medicine.disease Functional Independence Measure Confidence interval functional independence measure ROC Curve Research Design Brain Injuries outpatient Cohort Physical therapy prognosis Neurology (clinical) 0305 other medical science business 030217 neurology & neurosurgery |
Zdroj: | Worm, M S, Valentin, J B, Johnsen, S P, Nielsen, J F, Forchhammer, H B & Svendsen, S W 2021, ' Predictors of disability in adolescents and young adults with acquired brain injury after the acute phase ', Brain Injury, vol. 35, no. 8, pp. 893-901 . https://doi.org/10.1080/02699052.2021.1927183 |
ISSN: | 1362-301X 0269-9052 |
DOI: | 10.1080/02699052.2021.1927183 |
Popis: | AIM: To develop and validate a prediction model for disability among young patients with acquired brain injury (ABI) after the acute phase.METHODS: Within a nationwide cohort of 446 15-30-year-old ABI-patients, we predicted disability in terms of Glasgow Outcome Scale - Extended (GOS-E) RESULTS: Baseline assessment took place a median of 12 months post-ABI. Low GOS-E (range 1-8 (best)) and Functional Independence Measure (range 18-126 (best)) along with high mental fatigue (range 4-20 (worst)) predicted disability. The model showed high validity and performance with an area under the curve of 0.82 (95% confidence interval (CI) 0.77, 0.87) in the cross-validation and 0.81 (95% CI 0.73, 0.88) in the geographical validation.CONCLUSION: We developed and validated a parsimonious model which effectively predicted disability. The model may be useful to guide decision-making in outpatient neurorehabilitation clinics treating young patients with ABI. |
Databáze: | OpenAIRE |
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