Enteropathogens Associated with Acute and Persistent Diarrhea in BangladeshiChildren <5 Years of Age
| Autor: | R. Bradley Sack, Hafizur Rahman Chowdhury, M. Yunus, Anowar Hossain, Robert E. Black, Abdullah H Baqui, A. K. Siddique, Khaleda Haider, A. R. M. Abdul Alim |
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| Rok vydání: | 1992 |
| Předmět: |
Diarrhea
Longitudinal study medicine.medical_specialty Enterobacter Rural Health medicine.disease_cause Feces Rotavirus Internal medicine Epidemiology medicine Humans Immunology and Allergy Shigella Longitudinal Studies Bangladesh biology business.industry Cryptosporidium biology.organism_classification Infectious Diseases El Niño Child Preschool Immunology medicine.symptom business |
| Zdroj: | Journal of Infectious Diseases. 166:792-796 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/166.4.792 |
| Popis: | A longitudinal study of diarrhea was carried out from May 1988 to April 1989 by household surveillance of 705 children less than 5 years old in rural Bangladesh. Stool samples were examined for enteric pathogens at the beginning of each diarrheal episode. For persistent episodes, stool examination was repeated on days 15-17 of the illness. For each case of persistent diarrhea, stool samples from age-matched acute diarrheal and healthy controls were examined. Compared with healthy controls, cases of diarrhea were associated with Shigella species (P = .07) and rotavirus (P less than .05). Diffusely adherent Escherichia coli (P less than .05) and cryptosporidia (P = .07) were the only enteropathogens associated with persistent diarrhea in comparison with acute diarrhea. No more than 15% of children had the same class of pathogen identified from stool on both days 1-3 and days 15-17, indicating that persistent infection was uncommon. However, a different enteropathogen was frequently found on days 15-17, suggesting that sequential infection may be a cause of persistent diarrhea. |
| Databáze: | OpenAIRE |
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