Taking a Low Glycemic Index Multi-Nutrient Supplement as Breakfast Improves Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Autor: Di Li, Honghui Guo, Wenhua Ling, Peiwen Zhang
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Blood Glucose
Dietary Fiber
Male
type 2 diabetes mellitus
Body Mass Index
law.invention
Randomized controlled trial
low glycemic index
law
Insulin
Nutrition and Dietetics
Middle Aged
multi-nutrient supplement
Treatment Outcome
Glycemic index
Female
Dietary Proteins
medicine.symptom
lcsh:Nutrition. Foods and food supply
Adult
medicine.medical_specialty
Nutritional Status
lcsh:TX341-641
Motor Activity
Article
breakfast replacement
Young Adult
Internal medicine
Diabetes mellitus
Dietary Carbohydrates
medicine
Humans
Triglycerides
Aged
Breakfast
Glycemic
Food
Formulated
Glycated Hemoglobin
business.industry
Body Weight
Cholesterol
HDL
Type 2 Diabetes Mellitus
Cholesterol
LDL
medicine.disease
Dietary Fats
Confidence interval
Endocrinology
Diabetes Mellitus
Type 2
Glycemic Index
glycemic control
Energy Intake
business
Body mass index
Weight gain
Food Science
Zdroj: Nutrients, Vol 6, Iss 12, Pp 5740-5755 (2014)
Nutrients
Volume 6
Issue 12
Pages 5740-5755
ISSN: 2072-6643
Popis: Dietary therapy is the mainstay of treatment for diabetes. This study examined the effect of a low glycemic index (GI) multi-nutrient supplement, consumed in place of breakfast, on glycemic control in patients with type 2 diabetes mellitus (T2DM). A total of 71 participants were randomized at a 2:1 ratio into either a breakfast replacement group or a normal breakfast group for a 12-week interventional study. The primary outcome measure was change in hemoglobin A1c (HbA1c). Nutrition status and somatometry were studied as secondary outcomes. The breakfast replacement group displayed a −0.2% absolute reduction in HbA1c (95% CI (confidence interval), −0.38% to −0.07%, p = 0.004), while the HbA1c of the control group increased 0.3% (95% CI, 0.1% to 0.5%, p = 0.005). The baseline Mini Nutritional Assessment score for both groups was 26.0 and no significant changes occurred following intervention. However, there was a statistically significant difference in body mass index between the treatment and control groups (p = 0.032) due to the weight gain in the control group (increased 0.5 kg, 95% CI was 0.2 to 0.9, p = 0.007). These data suggest that breakfast replacement with a low GI multi-nutrient supplement can improve glycemic and weight control in T2DM.
Databáze: OpenAIRE
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