Taking a Low Glycemic Index Multi-Nutrient Supplement as Breakfast Improves Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial
Autor: | Di Li, Honghui Guo, Wenhua Ling, Peiwen Zhang |
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Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Blood Glucose
Dietary Fiber Male type 2 diabetes mellitus Body Mass Index law.invention Randomized controlled trial low glycemic index law Insulin Nutrition and Dietetics Middle Aged multi-nutrient supplement Treatment Outcome Glycemic index Female Dietary Proteins medicine.symptom lcsh:Nutrition. Foods and food supply Adult medicine.medical_specialty Nutritional Status lcsh:TX341-641 Motor Activity Article breakfast replacement Young Adult Internal medicine Diabetes mellitus Dietary Carbohydrates medicine Humans Triglycerides Aged Breakfast Glycemic Food Formulated Glycated Hemoglobin business.industry Body Weight Cholesterol HDL Type 2 Diabetes Mellitus Cholesterol LDL medicine.disease Dietary Fats Confidence interval Endocrinology Diabetes Mellitus Type 2 Glycemic Index glycemic control Energy Intake business Body mass index Weight gain Food Science |
Zdroj: | Nutrients, Vol 6, Iss 12, Pp 5740-5755 (2014) Nutrients Volume 6 Issue 12 Pages 5740-5755 |
ISSN: | 2072-6643 |
Popis: | Dietary therapy is the mainstay of treatment for diabetes. This study examined the effect of a low glycemic index (GI) multi-nutrient supplement, consumed in place of breakfast, on glycemic control in patients with type 2 diabetes mellitus (T2DM). A total of 71 participants were randomized at a 2:1 ratio into either a breakfast replacement group or a normal breakfast group for a 12-week interventional study. The primary outcome measure was change in hemoglobin A1c (HbA1c). Nutrition status and somatometry were studied as secondary outcomes. The breakfast replacement group displayed a −0.2% absolute reduction in HbA1c (95% CI (confidence interval), −0.38% to −0.07%, p = 0.004), while the HbA1c of the control group increased 0.3% (95% CI, 0.1% to 0.5%, p = 0.005). The baseline Mini Nutritional Assessment score for both groups was 26.0 and no significant changes occurred following intervention. However, there was a statistically significant difference in body mass index between the treatment and control groups (p = 0.032) due to the weight gain in the control group (increased 0.5 kg, 95% CI was 0.2 to 0.9, p = 0.007). These data suggest that breakfast replacement with a low GI multi-nutrient supplement can improve glycemic and weight control in T2DM. |
Databáze: | OpenAIRE |
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