Changes in the epidemiology of hepatitis B virus infection following the implementation of immunisation programmes in northeastern Greece
| Autor: | George Zacharakis, Fevronia Tzara, M. Papoutselis, E. Maltezos, E. Pouliou, John Koskinas, Kostantinos Papoutselis, N Vafiadis, Stamatia Kotsiou |
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| Rok vydání: | 2009 |
| Předmět: |
Hepatitis B virus
HBsAg education.field_of_study Pediatrics medicine.medical_specialty Epidemiology business.industry Population Public Health Environmental and Occupational Health Hepatitis B medicine.disease_cause medicine.disease Vaccination Virology medicine Seroprevalence Young adult education business |
| Zdroj: | Web of Science Scopus-Elsevier |
| ISSN: | 1560-7917 |
| DOI: | 10.2807/ese.14.32.19297-en |
| Popis: | The objective of this study was to investigate changes in the epidemiology of hepatitis B virus infection in the general population and selected groups of immigrants in the region of northeastern Greece over the last decade in relation to the introduction of hepatitis B vaccination programmes. Two population-based seroprevalence surveys were carried out during the years 1992-1994 and 1998-2006. In total, 25,105 individuals were tested for the presence of hepatitis B virus markers: HBsAg, anti-HBs and anti-HBc. Childhood/adolescence immunisation programmes began early in 1994 in selected groups of immigrants and were complemented by the national vaccination programme in 1998. Between 1992-1994 and 1998-2006, the HBsAg carrier rate declined from 5.4% [95% CI: 4.5-5.9] in adults (20-60 years old) and 1.9% [95% CI: 1.6-2.4] in children/adolescents (5-19 years old) of indigenous residents to 3.4% [95% CI: 2.9-3.8] and 0.6% [95% CI: 0.2-1.4] respectively (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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