Hyaluronic Acid Behavior in the Lamina Propria of the Larynx with Advancing Age
| Autor: | Carlos Eduardo Fonseca-Alves, Sergio Augusto Rodrigues, Anete Branco, Alexandre Todorovic Fabro, Regina Helena Garcia Martins |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Larynx Aging Lamina Pathology medicine.medical_specialty Vocal Cords Tissue Culture Techniques chemistry.chemical_compound Hyaluronic acid Cadaver medicine Humans Prospective Studies Hyaluronic Acid Aged Lamina propria Acid level Mucous Membrane business.industry Mucous membrane Anatomy Middle Aged medicine.anatomical_structure Otorhinolaryngology chemistry Homogeneous Case-Control Studies Vocal folds Surgery business |
| Zdroj: | Otolaryngology–Head and Neck Surgery. 151:652-656 |
| ISSN: | 1097-6817 0194-5998 |
| Popis: | ObjectivesTo analyze the hyaluronic acid behavior in the lamina propria of the larynx with advancing age.Study DesignProspective study.SettingUNESP-Univ Estadual Paulista, Botucatu Medical School, Brazil.Subjects and MethodsThirty vocal folds were obtained at necropsy from 10 adult males (30–50 years old) and 20 geriatric males (10: 60–75 years old; 10: over 76 years old). Midmembranous vocal fold sections were subjected to immunohistochemical reactions. Digital imaging software (ImageJ) was used to quantify the hyaluronic acid distribution over the lamina propria of vocal folds, from superficial to deep layers.ResultsHyaluronic acid distribution was homogeneous for the larynges, at both superficial and deep layers (41.6 and 38.5, respectively). For both 30- to 50-year-old men geriatric age groups, hyaluronic acid level was lower at both layers.ConclusionHyaluronic acid level in the lamina propria of the larynx of geriatric men decreases with advancing age at both layers of the lamina. |
| Databáze: | OpenAIRE |
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