3D-printed microchip electrophoresis device containing spiral electrodes for integrated capacitively coupled contactless conductivity detection

Autor:	Jacob B. Nielsen, Gregory P. Nordin, Brenda M. C. Costa, Aline Guadalupe Coelho, Michael J. Beauchamp, José Alberto Fracassi da Silva, Adam T. Woolley
Rok vydání:	2021
Předmět:	Materials science Fabrication business.industry chemistry.chemical_element Conductivity Biochemistry Article Analytical Chemistry chemistry.chemical_compound chemistry Electrode Optoelectronics Digital Light Processing Gallium Spiral (railway) business Electrical conductor Ethylene glycol
Zdroj:	Anal Bioanal Chem
ISSN:	1618-2650 1618-2642
DOI:	10.1007/s00216-021-03494-2
Popis:	In this work, we demonstrate for the first time the design and fabrication of microchip electrophoresis devices containing cross-shaped channels and spiral electrodes around the separation channel for microchip electrophoresis and capacitively coupled contactless conductivity detection. The whole device was prepared in a digital light processing-based 3D printer in poly(ethylene glycol) diacrylate resin. Outstanding X-Y resolution of the customized 3D printer ensured the fabrication of 40-μm cross section channels. The spiral channels were filled with melted gallium to form conductive electrodes around the separation channel. We demonstrate the applicability of the device on the separation of sodium, potassium, and lithium cations by microchip electrophoresis. Graphical abstract.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf66ede19242cceda01dc4c353c1d7 https://doi.org/10.1007/s00216-021-03494-2 Zobrazit plný text záznamu Full text from SpringerLink