Activation of rabbit brain microsomal (Na+ + K+)-dependent ATPase by a leukocytic product
| Autor: | Gale W. Rafter, Roger S. Riley |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_treatment
ATPase Biophysics Cellophane Biochemistry law.invention chemistry.chemical_compound law Microsomes Leukocytes medicine Animals Phenol Molecular Biology Adenosine Triphosphatases ATP phosphohydrolase Protease biology Tissue Extracts Activator (genetics) Sodium Brain Blood Proteins Trypsin Molecular biology Enzyme Activation chemistry Potassium Microsome biology.protein Rabbits medicine.drug |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - General Subjects. 381:120-127 |
| ISSN: | 0304-4165 |
| DOI: | 10.1016/0304-4165(75)90194-4 |
| Popis: | The properties of a (Na + + K + )-dependent ATPase (ATP phosphohydrolase, EC 3.6.1.3) activator contained in leukocytic extracts was investigated. Intact polymorphonuclear leukocytes release the activator in a time- and temperature-dependent process. It is non-dialyzable through cellophane: inactivated by protease, trypsin, or phenol; contains essential sulfhydryl groups; and is heat and acid labile. Treatment of ATPase with the activator and subsequent removal of the activator from mixtures did not reverse the ATPase activation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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