Effect of Vitamin D Level on Clinical Outcomes in Patients Undergoing Left Ventricular Assist Device Implantation

Autor: Antone Tatooles, Gardner Yost, Fadi Abou Obeid, Geetha Bhat, Erin Drever
Rok vydání: 2018
Předmět:
Zdroj: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 33(6)
ISSN: 1941-2452
Popis: BACKGROUND Vitamin D is an important hormone that regulates cardiac myocyte function. Low levels contribute to the development of cardiovascular disease and have been implicated in immune function and the inflammatory cascade. Patients who undergo left ventricular assist device (LVAD) implantation are at risk for driveline infection, stroke, and gastrointestinal (GI) bleeding. We investigated whether serum 25-hydroxy (25-OH) vitamin D levels affect clinical outcomes after LVAD. METHODS 212 patients who underwent LVAD implantation between 2010 and 2015 were included. We measured preoperative 25-OH vitamin D level and postoperative adverse events during the first year. Vitamin D level was classified into 3 categories: normal (>30 ng/mL), insufficient (20-30 ng/mL), and deficient (
Databáze: OpenAIRE