Epidemiology of human papillomavirus infection and abnormal cytologic test results in an urban adolescent population
| Autor: | Lauri E. Markowitz, Mary K. Sawyer, Carolyn M. Black, Elizabeth R. Unger, Emilia H. Koumans, Trudee A. Tarkowski, John R. Papp, Antonya Pierce |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis Georgia Adolescent Genotype Urban Population Sexual Behavior Population Polymerase Chain Reaction Uterine Cervical Diseases Risk Factors Cytology Surveys and Questionnaires Epidemiology medicine Prevalence Immunology and Allergy Humans Human papillomavirus education Cervix Papillomaviridae Cytologic Test Gynecology Vaginal Smears education.field_of_study Genitourinary system business.industry Obstetrics Papillomavirus Infections Oncogene Proteins Viral Infectious Diseases medicine.anatomical_structure Multivariate Analysis Capsid Proteins Female business |
| Zdroj: | The Journal of infectious diseases. 189(1) |
| ISSN: | 0022-1899 |
| Popis: | We determined the prevalence of and the risk factors for human papillomavirus (HPV) infection and abnormal cytologic test results in 312 adolescent girls (mean age 16.1 years). Subjects had a median of 2 years of sexual activity and 4 lifetime sex partners. Cervical HPV was detected by use of L1-consensus polymerase chain reaction in 64% of subjects; half of those with HPV had >1 type and 77% had >/=1 high-risk type. Independent risk factors for HPV were lifetime number of sex partners age of partner and douching. Cytologic abnormalities were common (20.9% of subjects had atypical squamous cells of uncertain significance and 17.0% had high- or low-grade squamous intraepithelial lesions) and were significantly associated with detection of HPV (P = .0001); however most (51.6%) subjects with HPV had normal cytologic test results. (excerpt) |
| Databáze: | OpenAIRE |
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