Vaginal progesterone as luteal phase support in an IVF/GIFT programme
| Autor: | J. Leeton, Peter Rogers, J.A. Krapez, D.W. Polson |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pessary
Adult medicine.medical_specialty Menotropins medicine.medical_treatment Fertilization in Vitro Luteal phase Luteal Phase Clomiphene Pregnancy Medicine Humans Prospective Studies Gamete intrafallopian transfer reproductive and urinary physiology Luteal support Progesterone Gynecology business.industry Obstetrics Pregnancy Outcome Obstetrics and Gynecology Pessaries medicine.disease Embryo Transfer Embryo transfer Gamete Intrafallopian Transfer Pregnancy Ectopic Pregnancy rate Administration Intravaginal Reproductive Medicine Female business hormones hormone substitutes and hormone antagonists |
| Zdroj: | European journal of obstetrics, gynecology, and reproductive biology. 46(1) |
| ISSN: | 0301-2115 |
| Popis: | To determine whether luteal phase support with vaginal progesterone could improve pregnancy rates in our IVF/GIFT programme, we performed a prospective randomised controlled study. After stimulation with clomiphene citrate/human menopausal gonadotrophin, 123 women received no luteal support and 122 received progesterone pessaries 100 mg b.d. from 48 hours prior to embryo transfer and continued throughout the luteal phase. There was no difference in the pregnancy rate following IVF/ET (6/58 and 10/58 for the pessary and control group respectively), but a significantly higher rate was noted for GIFT (13/34 and 5/42 for the pessary and control group respectively; P less than 0.05). Of interest, only one of the 19 pregnancies using luteal support was extra-uterine, compared with 6/15 in the control group. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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