Synthesis of 4-Imidazolidinones from Diamides and Ethynyl Benziodoxolones via Double Michael-Type Addition: Ethynyl Benziodoxolones as Electrophilic Ynol Synthons

Autor:	Ayaka Shimizu, Atsushi Shibata, Takashi Kano, Yuuichi Kumai, Ryouhei Kawakami, Hiroyoshi Esaki, Kazuaki Fukushima, Norihiro Tada, Akichika Itoh
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic Letters. 24:8859-8863
ISSN:	1523-7052 1523-7060
Popis:	The moiety of 4-imidazolidinone is an important structural motif in organic synthesis and medicinal chemistry. We present the synthesis of 4-imidazolidinones from various diamides with ethynyl benziodoxolones through double Michael-type addition, which is an unprecedented reaction mode for hypervalent alkynyl iodine compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbb85bed72a868ae9e00b8dc765610a https://doi.org/10.1021/acs.orglett.2c03648 Zobrazit plný text záznamu